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Both agents mimic endogenous GLP-1 but differ in pharmacokinetics: liraglutide requires daily injection, whereas semaglutide's extended half-life allows weekly dosing

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Future RCTs should test various GLP-1RAs across broader AUD populations, standardize outcomes, and explore body weights moderating role

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Eur J Med Chem 2022;230:114119.ArticlePubMed 213

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